Clomiphene Dosage: What You Need to Know Before Taking It
When it comes to clomiphene, a selective estrogen receptor modulator used to trigger ovulation in women struggling with infertility. Also known as clomiphene citrate, it’s one of the most common first-line treatments for women who don’t ovulate regularly. Unlike hormonal injections, clomiphene is taken as a pill—simple, affordable, and widely prescribed. But getting the dosage wrong can mean no results… or unwanted side effects.
Most doctors start with a clomiphene dosage of 50 mg per day for five days, starting on day 3 to 5 of the menstrual cycle. If ovulation doesn’t happen after a cycle, the dose might go up to 100 mg. Going higher than that rarely helps and increases the risk of side effects like hot flashes, mood swings, or blurred vision. It’s not a one-size-fits-all drug—your weight, hormone levels, and medical history all play a role. Some women respond to 25 mg; others need 150 mg. The key is starting low and adjusting slowly under supervision.
Clomiphene doesn’t work for everyone. It’s most effective for women with polycystic ovary syndrome (PCOS) or irregular cycles caused by low hormone signals from the brain. But if your ovaries are already exhausted, or if your partner has severe sperm issues, clomiphene alone won’t fix it. That’s why it’s often paired with timed intercourse or IUI. And while it’s not a miracle drug, it’s helped millions of women conceive without resorting to expensive IVF.
Side effects are usually mild, but they’re real. Some women report headaches, nausea, or bloating. A small percentage develop ovarian hyperstimulation syndrome—swollen, painful ovaries that need medical attention. Long-term use (more than six cycles) isn’t recommended because it may affect cervical mucus and the uterine lining. And yes, it slightly increases the chance of twins—about 1 in 10 pregnancies.
Clomiphene is also used off-label in men to boost testosterone by tricking the brain into making more LH and FSH. In those cases, dosages are lower and taken less frequently. But whether you’re a woman trying to get pregnant or a man looking to restore natural hormone levels, the same rule applies: never self-prescribe. This isn’t a supplement. It’s a powerful drug that changes your body’s signaling system.
Below, you’ll find real-world stories, dosage breakdowns, and comparisons with other fertility treatments—all backed by clinical experience and patient reports. Whether you’re just starting out or wondering why your last cycle didn’t work, the posts here will help you ask the right questions.
